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Jennifer Munkert Selected Research

Cardenolides

4/2021Cytotoxicity of glucoevatromonoside alone and in combination with chemotherapy drugs and their effects on Na+,K+-ATPase and ion channels on lung cancer cells.
1/2021In vitro and in vivo antileishmanial activity of β-acetyl-digitoxin, a cardenolide of Digitalis lanata potentially useful to treat visceral leishmaniasis.
1/2021Digitoxigenin presents an effective and selective antileishmanial action against Leishmania infantum and is a potential therapeutic agent for visceral leishmaniasis.
11/2018Cytotoxicity of AMANTADIG - a semisynthetic digitoxigenin derivative - alone and in combination with docetaxel in human hormone-refractory prostate cancer cells and its effect on Na+/K+-ATPase inhibition.
1/2018Cytotoxic and cytostatic effects of digitoxigenin monodigitoxoside (DGX) in human lung cancer cells and its link to Na,K-ATPase.
1/2018Cardiac Glycoside Glucoevatromonoside Induces Cancer Type-Specific Cell Death.
2/2017A new semisynthetic cardenolide analog 3β-[2-(1-amantadine)- 1-on-ethylamine]-digitoxigenin (AMANTADIG) affects G2/M cell cycle arrest and miRNA expression profiles and enhances proapoptotic survivin-2B expression in renal cell carcinoma cell lines.

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Jennifer Munkert Research Topics

Disease

10Neoplasms (Cancer)
04/2021 - 09/2014
4Lung Neoplasms (Lung Cancer)
04/2021 - 01/2018
4Heart Diseases (Heart Disease)
01/2021 - 01/2018
3Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
04/2021 - 01/2018
2Visceral Leishmaniasis (Kala Azar)
01/2021 - 01/2021
2Heart Failure
06/2020 - 11/2018
2Prostatic Neoplasms (Prostate Cancer)
11/2018 - 08/2017
2Renal Cell Carcinoma (Grawitz Tumor)
08/2017 - 02/2017
1Infections
01/2021
1Human Influenza (Influenza)
10/2020
1Carcinoma (Carcinomatosis)
11/2018
1Cardiovascular Diseases (Cardiovascular Disease)
02/2017

Drug/Important Bio-Agent (IBA)

7CardenolidesIBA
04/2021 - 02/2017
7Cardiac GlycosidesIBA
06/2020 - 02/2017
5Adenosine Triphosphatases (ATPase)IBA
04/2021 - 08/2017
5DigitoxigeninIBA
01/2021 - 02/2017
3Pharmaceutical PreparationsIBA
04/2021 - 01/2018
3glucoevatromonosideIBA
04/2021 - 08/2017
2DigitoxinFDA Link
01/2021 - 02/2017
2Antiviral Agents (Antivirals)IBA
10/2020 - 04/2019
23- (2- (1- amantadine)- 1- one- ethylamine)digitoxigeninIBA
11/2018 - 02/2017
2Vinblastine (Vinblastine Sulfate)FDA Link
01/2015 - 09/2014
2Vincristine (Oncovin)FDA LinkGeneric
01/2015 - 09/2014
2Secologanin Tryptamine Alkaloids (Alseroxylon)FDA Link
01/2015 - 09/2014
1Ion Channels (Ion Channel)IBA
04/2021
1Therapeutic UsesIBA
01/2021
1miltefosine (Impavido)IBA
01/2021
1Pentetic Acid (DTPA)FDA LinkGeneric
12/2019
1Proteins (Proteins, Gene)FDA Link
12/2019
1Paclitaxel (Taxol)FDA LinkGeneric
04/2019
1AndrogensIBA
11/2018
1Cyclin B1IBA
11/2018
1Hormones (Hormone)IBA
11/2018
1Docetaxel (Taxotere)FDA Link
11/2018
1SurvivinIBA
11/2018
1digitoxigenin monodigitoxosideIBA
01/2018
1LigandsIBA
01/2018
1Cytostatic AgentsIBA
01/2018
1Amantadine (Aman)FDA LinkGeneric
02/2017
1ethylamineIBA
02/2017
1MicroRNAs (MicroRNA)IBA
02/2017

Therapy/Procedure

3Therapeutics
04/2021 - 08/2017
1Drug Therapy (Chemotherapy)
04/2021